The interactions of electrons and ions are among the most fundamental processes that occur in laboratory and astrophysical plasmas. The understanding of these collisions are essential for diagnosing and modeling plasmas encountered in controlled fusion experiments, plasma processing, and astrophysics. In addition to the application of studying plasma dynamics, electron-impact ionization is interesting from the view of fundamental physics, as it is a challenging quantum many-body problem. As theoretical techniques used to predict this process are refined and evolved, the need for evermore exacting experimental verifications of these calculations continue. The ionization of atomic and molecular ions by electrons is measured by a number of groups around the world, employing both heavy-ion storage rings as well as single-pass beam-beam experiments. The experimental emphasis has been two-fold: first, to produce the collision data needed to support plasma science, and second, to explore interesting physical mechanisms of ionization while providing stringent benchmarks for theoretical predictions. Some recent results on electron-impact ionization of both atomic and molecular ions will be highlighted.